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Celebrex (celecoxib) relieves pain and inflammation by blocking COX-2 enzymes, which are responsible for the synthesis of prostaglandins (prostaglandins are released during inflammation and elevate body temperature and make nerve endings more sensitive to pain transmission). You can reach us at 1 888-854-4949 1 888-854-4848 (Monday - Friday 9am to 5pm MST) Customer Support. The usual dose is 200 to 400-mg. For the best results, take these pills at the same time every day too much Celebrex. So throw in the cost of a Doc visit. Do this even if there are no signs of discomfort or poisoning. In general, consulting the doctor is always recommended before investing in a wheelchair for your loved one.. By law pharmacies have to put at least a one year expiration date on all drug labels. See full prescribing information for CELEBREX. You may also have difficulty breathing and feel faint. WARNING: CARDIOVASCULAR AND GASTROINTESTINAL RISKS. 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